Chemical constituents of Phyllanthus amaus
- Author:
Wei SUN
1
Author Information
1. Central Hospital of Fengxian District
- Publication Type:Journal Article
- Keywords:
4-hydroxy-3-methoxy-benzoic acid;
Apigenin;
Oleanolic acid;
Phyllanoside;
Phyllanthus amarus schum. Et thonn
- From:
Chinese Traditional and Herbal Drugs
2012;43(1):23-26
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the chemical constituents of Phyllanthus amarus. Methods Chromatography on silica gel column, Sephadex LH-20 columm, recrystallization, and preparative HPLC technique were used to isolate and purify the compounds. Spectroscopic methods including UV, IR, EI-MS, 1H-NMR, 13C-NMR, HMQC, and HMBC were used to elucidate the structures of compounds. Results Nine compounds were obtained and identified as palmitic acid (1), 4-hydrobenzal dehyde (2), oleanolic acid (3), stigmast-5-en-3-ol, oleate (4), 4-hydroxy-3-methoxy-benzoic acid (5), daucosterol (6), apigenin (7), luteolin (8), and phyllanoside (9). Conclusion Compound 9 is a new compound, named phyllanoside. Compounds 4-8 are isolated from the plant for the first time.
