Principal component analysis of Baihuasheshecao Injection by UPLC-QTOF-MS
10.7501/j.issn.0253-2670.2013.07.011
- Author:
Ya-Zhong ZHANG
1
Author Information
1. Anhui Institute for Food and Drug Control
- Publication Type:Journal Article
- Keywords:
Baihuasheshecao (Hedyotis Diffusae Herba) Injection;
Flavonoids;
Organic acids;
Principal component analysis;
Substantial base;
UPLC-QTOF-MS
- From:
Chinese Traditional and Herbal Drugs
2013;44(7):829-833
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the difference of substantial base of Baihuasheshecao (Hedyotis Diffusae Herba) Injection (BSCI) within the nationwide. Methods: To determine 16 batches of samples by UPLC-QTOF-MS and analyze the data according to a variety of retention time and m/z by principal component analysis (PCA). Results: The results showed that the difference itself was smaller but between each other was bigger among the different enterprises. Seven markers greatly impacted on the components through loading plot analysis were found. Conclusion: BSCIs from different enterprises within nationwide are not only obviously different in color but also different in substantial base, which especially indicates the content of flavonoids and organic acids.
