Chemical constituents from Swertia mussotii
10.7501/j.issn.0253-2670.2013.08.004
- Author:
Cui-Ting LUO
1
Author Information
1. Institute of Traditional Chinese Medicine and Natural Product
- Publication Type:Journal Article
- Keywords:
1, 3, 7-trihydroxyxanthone;
Gentiolactone;
Mangiferin;
Olenaolic acid;
Swertia mussotii Franch.
- From:
Chinese Traditional and Herbal Drugs
2013;44(8):942-946
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents of Swertia mussotii. Methods: Various chromatographic methods were employed to isolate the compounds and their structures were established by spectroscopic analysis. Results: Nineteen compounds were isolated from 75% ethanol extract of S. mussotii and identified as 1-hydroxyl-3, 4, 7, 8-tetramethoxyxanthone (1), 1, 7- dihydroxyl-3-methoxyxanthone (2), 1, 3, 7-trihydroxyxanthone (3), 1, 3, 7, 8-tetrahydroxyxanthone (4), 1, 3, 8-trihydroxyl-7- methoxyxanthone (5), 1, 3-dihyfroxyl-7, 8-dimethoxyxanthone (6), 1, 5, 8-trihydroxyl-3, 4-dimethoxyxanthone (7), 1-hydroxyl-3, 4, 5, 8-tetramethoxyxanthone (8), 1-hydroxyl-3, 5, 8-trimethoxyxanthone (9), (S)-(+)-gentiolactone (10a), (R)-(-)-gentiolactone (10b), 1, 8-dihydroxyl-3, 7-dimethoxyxanthone (11), 1-hydroxyl-3, 7, 8-trimethoxyxanthone (12), 1, 7-dihydroxyl-3, 8-dimethoxyxanthone (13), 1, 7, 8-trihydroxyl-3-methoxyxanthone (14), 1, 3, 5, 8-tetrahydroxyxanthone (15), 1, 7-dihydroxyl-3, 4, 8-trimethoxyxanthone (16), mangiferin (17), and oleanolic acid (18), respectively. Conclusion: Compounds 1-9 are firstly isolated from S. mussotii. Compounds 10a and 10b are firstly isolated from the plants in Swertia L.
