Chemical constituents of Croton crassifolius
10.7501/j.issn.0253-2670.2013.10.003
- Author:
Yao-Kui ZHU
1
Author Information
1. Department of Obstetrics and Gynecology
- Publication Type:Journal Article
- Keywords:
Crassifolius acid;
Crassifolius ester;
Croton crassifolius Geiseler;
Lupeol;
Stigmasterol
- From:
Chinese Traditional and Herbal Drugs
2013;44(10):1231-1236
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents of Croton crassifolius. Methods: A number of methods, such as extraction, chromatography on silica gel, and recrystallization, were utilized to isolate and purify the ethanol extract from C. crassifolius, and the structures of the compounds isolated were identified by physicochemical properties and spectral analyses. Results: Ten compounds were isolated and identified as cyperenoic acid (1), β-sitosterol (2), lupeol (3), chettaphanin II (4), 9-[2-(2(5H)-furanone-4-yl) ethyl]-4, 8, 9-trimethyl-1, 2, 3, 4, 5, 6, 7, 8-octahydro-naphthalene-4-carboxylic acid (5), acetyl aleuritolic acid (6), epitaraxerol (7), 9-[2-(2(5H)-furanone-4-yl) ethyl]-4, 8, 9-trimethyl-1, 2, 3, 4, 5, 6, 7, 8-octahydronaphthalene-4-carboxylic ester (8), teucvidin (9), and stigmasterol (10). Conclusion: Compounds 5 and 8 are newly-discovered compounds, named as crassifolius acid and crassifolius ester, and compounds 4, 6, and 7 are isolated from this plant for the first time.
