Chemical constituents from seeds of Datura metel (I)
10.7501/j.issn.0253-2670.2013.14.003
- Author:
Bing-You YANG
1
Author Information
1. Key Laboratory of Chinese Materia Medica
- Publication Type:Journal Article
- Keywords:
Cannabisin E;
Cannabisin F;
Datura metel L.;
Daturaolone;
Fraxetin
- From:
Chinese Traditional and Herbal Drugs
2013;44(14):1877-1880
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents in the seeds of Datura metel. Methods: The constituents were isolated and purified by silica gel, ODS, and Sephadex LH-20 column chromatographies as well as HPLC. Their chemical structures were elucidated on the basis of spectral data. Results: The compounds were isolated from the EtOAc fraction of D. metel extract and identified as cannabisin D (1), cannabisin E (2), cis-cannabisin E (3), cannabisin F (4), cannabisin L (5), cannabisin G (6), grossamide K (7), hyoscyamilactol (8), daturaolone (9), N-trans-feruloyl tryptamine (10), and fraxetin (11), respectively. Conclusion: Compounds 2 and 4 are firstly isolated from the plants in Solanaceae, compounds 1, 3, and 5-7 are firstly isolated from the plants in genus Datura L. and compounds 8-11 are isolated from this plant for the first time.
