Alkaloids from roots of Cocculus orbiculatus var. mollis
10.7501/j.issn.0253-2670.2013.17.003
- Author:
Jian-Zhong WANG
1
Author Information
1. West China School of Pharmacy
- Publication Type:Journal Article
- Keywords:
1, 2-dehydroapateline;
BBI alkaloid;
Cocculus orbiculatus (L.) DC. var. mollis (Wall. ex Hook. f. et Thoms.) Hara;
Orbiculatinine;
trilobine
- From:
Chinese Traditional and Herbal Drugs
2013;44(17):2350-2353
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the alkaloid compounds in the roots of Cocculus orbiculatus var. mollis. Methods: The compounds were isolated by silica gel chromatography, and their structures were established by spectroscopic methods. Results: A novel cocsolines-type bisbenzylisoquinoline alkaloid named orbiculatinine (1), along with three known compounds (+) 1, 2- dehydroapateline (2), trilobine (3), and isotrilobine (4), were isolated. Conclusion: Compound 1 is a new compound named orbiculatinine. Compounds 2-4 are isolated from this plant for the first time.
