Chemical constituents from Cardamine leucantha
10.7501/j.issn.0253-2670.2013.19.005
- Author:
Cong-Cong ZHENG
1
Author Information
1. School of Pharmaceutical Science and Technology
- Publication Type:Journal Article
- Keywords:
Cardamine L.;
Cardamine leucantha O. E. Schulz;
Esculetin;
Indole-3-carboxylic acid;
Sitost-5-ene-3β, 7α-diol
- From:
Chinese Traditional and Herbal Drugs
2013;44(19):2657-2660
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents in the whole herbs of Cardamine leucantha. Methods: The chemical constituents were isolated and purified via silica gel, polyamide, D-101 macroperous resin, and Sephadex LH-20 column chromatography. Their structures were determined on the basis of spectral analysis and physicochemical properties. Results: Fourteen compounds were isolated and identified, covering three simple indoles: indole-3-carboxylic acid (1), 6-hydroxyindole-3-carboxylic acid (2), and 6-hydroxyindole-3-carboxylic acid-6-O-β-D-glucopyranoside (3); two coumarins: esculetin (4) and esculin (5); seven steroids: 3-O-(p-coumaroyl)-β-sitosterol (6), β-sitosterol (7), 5α, 8α-epidioxyergosta-6, 22-dien-3β-ol (8), 5α, 8α-epidioxyergosta-6, 9 (11), 22-trien-3β-ol (9), sitost-5-ene-3β, 7α-diol (10), β-sitosteryl-3β-glucopyranoside-6'-O-palmitate (11), and daucosterol (12); and two phenolic compounds: p-hydroxybenzoic acid (13) and vanillic acid (14). Conclusion: All the compounds are isolated from the plants in Cardamine L. for the first time.
