Chemical constituents in herbs of Bryophyllum pinnatum
10.7501/j.issn.0253-2670.2013.19.002
- Author:
Yan-Ying YE
1
Author Information
1. School of Traditional Chinese Materia Medica
- Publication Type:Journal Article
- Keywords:
Anti-allergy;
Bryophyllum pinnatum (L. f.) Oken;
Bryophylluside;
Crassulaceae;
Kaempfrol;
Lignans
- From:
Chinese Traditional and Herbal Drugs
2013;44(19):2642-2646
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To isolate and identify the chemical constituents from the herbs of Bryophyllum pinnatum. Methods: The compounds were isolated by chromatography on silica gel and Sephadex LH-20 columns and preparative TLC. The structures of the isolated compounds were elucidated based on spectroscopic data and chemical properties. The anti-allergic activities of the compounds were evaluated by RBL-2H3 cells. Results: Six compounds were isolated from the herbs of B. pinnatum. Their structures were identified as bryophylluside (1), kaempfrol (2), rutin (3), quercetin 3-O-α-L-arabinopyranosyl (1→2) α-L-rhamnopyranoside (4), quercitrin (5), and β-sitosterol (6). Conclusion: Compound 1 is a new lignan, and lignans are first isolated from B. pinnatum. Kaempfrol is one of the main anti-allergic active compounds in B. pinnatum.
