A new nortriterpenoid from Sambucus williamsii
10.7501/j.issn.0253-2670.2013.19.001
- Author:
Meng-Meng XU
1
Author Information
1. Nanjing University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
3-oxo-oleanolic acid;
Betulinic acid;
Nortriterpenoids;
Sambucus williamsii Hance;
Sambucusan A
- From:
Chinese Traditional and Herbal Drugs
2013;44(19):2639-2641
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents in 60% ethanol extract from the stems of Sambucus williamsii. Methods: Six compounds were isolated and purified by macroporous resin D-101, silica gel, Sephadex LH-20, Toyopearl HW-40, ODS column chromatographies, and RP-HPLC. Results: Their structures were elucidated by spectroscopic methods and identified as 23-hydroxy-3-oxo-28-nor-12, 16-dien oleanane (1), 3-oxo-oleanolic acid (2), oleanolic acid (3), betulinic acid (4), palmitic acid (5), and 1-octacosanol (6). Conclusion: Compound 1 is a new nortriterpenoid named sambucusan A. Compounds 2 and 6 are isolated from this plant for the first time.
