Chemical constituents from Achillea alpina
10.7501/j.issn.0253-2670.2013.20.005
- Author:
Rui-Ze ZHANG
1
Author Information
1. Department of Natural Products Chemistry
- Publication Type:Journal Article
- Keywords:
(±)-lariciresinol;
(+)- syringaresinol;
Achillea alpina L.;
Epifriedelanol;
Spinasterol
- From:
Chinese Traditional and Herbal Drugs
2013;44(20):2812-2815
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents from the aerial parts of Achillea alpina. Methods: The compounds were isolated and purified by various chromatographic techniques and their structures were characterized on the basis of physicochemical properties and their spectral analyses. Results: Eleven compounds were isolated. Their structures were identified as epifriedelanol (1), spinasterol (2), β-sitosterol (3), 5, 6-epoxy-24(R)-methylcholesta-7, 22-dien-3β-ol (4), β-daucosterol (5), schensianol A (6), negunfurol (7), (3S, 5S, 8R)-3, 5-dihydroxymegastigma-6, 7-dien-9-one (8), saropeptate (9), (+)-syringaresinol (10), and (±)-lariciresinol (11). Conclusion: All the compounds are isolated from the aerial parts of A. alpina for the first time, and compounds 1, 2, 4, 6-11 are reported to obtain from the plants in Achillea L. for the first time.
