Chemical constituents from leaves of Datura metel (I)
10.7501/j.issn.0253-2670.2013.20.003
- Author:
Bing-You YANG
1
Author Information
1. Key Lab. of Traditional Chinese Med. and Natl. Med. Efficacy Mat. Base Res. in Heilongjiang Province
- Publication Type:Journal Article
- Keywords:
Anoectochine;
Congmuyaglyeoside I;
L-tryptophan;
Leaves of Datura metel;
N-butyl-O-α-D-fructofuranosidase
- From:
Chinese Traditional and Herbal Drugs
2013;44(20):2803-2807
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents in the leaves of Datura metel. Methods: The chemical constituents of ethanol extract from the leaves of D. metel were isolated and purified by chromatography over silica gel, AB-8 macroperous resin, ODS, Sephadex LH-20 columns, and RP-preparative HPLC. The structures were elucidated on the basis of physicochemical properties and spectral data analyses. Results: Forteen compounds were isolated and identified as naphthisoxazol A (1), congmuyaglyeoside I (2), L-tryptophan (3), quercetin3-O-2-(E-caffeoyl)-α-larabinopyranosyl- (1→2)-β-D-glucopyranoside-7-O-β-D-glucoside (4), n-butyl-O-α-D-fructofuranosidase (5), anoectochine (6), dihydrovomifoliol-O-β-D-glucoside (7), (6S, 7E, 9S)-9- [(β-D-glucopyranosyl)-oxy] megastigma-4, 7-dien-3-one (8), kaepmferol-3, 7-di-O-β-D-glucopyranoside (9), kaempferol-7-O-β-D-glucoside (10), quercetin-7-O-glucoside (11), (6S, 9R)-6-hydroxy-3-ketone-α-violet-grape alcohol-9-O-β-D-glucopyranoside (12), stigmasterol (13), and stigmasterol-3-O-β-D-glucoside (14). Conclusion: Compounds 1-8 are firstly found in the plants of Solanaceae.
