Chemical constituents and their anti-oxidative activiities of Kadsura coccinea
10.7501/j.issn.0253-2670.2013.21.005
- Author:
Jae-Ho YEON
1
Author Information
1. Department of Natural Medicinal Chemistry
- Publication Type:Journal Article
- Keywords:
Anti-oxidation;
Ethyl shikimate;
Kadsura coccinea (Lem.) A. C. Smith;
Methyl shikimate;
Protocatechuic acid
- From:
Chinese Traditional and Herbal Drugs
2013;44(21):2969-2973
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents and their anti-oxidative activities of Kadsura coccinea. Methods: The compounds were isolated and purified by column chromatography. The structures were determined by means of physicochemical properties and spectroscopic analyses. The anti-oxidative activity was studied by DPPH methods. Results: Fourteen compounds were separated and identified as micrandilactone C (1), 3, 4-dimethoxy phenyl-α-D-glucopyranoside (2), salidroside (3), schisanhenol (4), protocatechuic acid (5), ethyl shikimate (6), shikimic acid (7), 5-O-β-D-glucopyranosylgentisic acid (8), syringic acid (9), 1, 2-benzenedicarboxylic acid-dibuty ester (10), benzyl-O-β-D-glucopyranoside (11), 4-O-β-D-glucopyranosylvanillic acid (12), syringaldehyde (13), and methyl shikimate (14). Compounds 5, 6, and 14 had the anti-oxidative activities. Conclusion: Compounds 2, 4, 6, and 8-14 are firstly isolated from K. coccinea. Compounds 5, 6, and 14 have the certain prospects in the development of natural anti-oxidative agents.