Detoxicity effect of hepatotoxicity of Tripterygium wilfordii by compatibility mechanism based on "diversity restriction" theory
10.7501/j.issn.0253-2670.2014.18.026
- Author:
Jing ZHANG
1
Author Information
1. Anhui University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Detoxicity by compatibility;
Diversity restriction;
Hepatotoxicity;
Toxicity restriction by strengthening the body resistance;
Triptergium wilfordii Hook. f.
- From:
Chinese Traditional and Herbal Drugs
2014;45(18):2711-2715
- CountryChina
- Language:Chinese
-
Abstract:
Tripterygium wilfordii as the preferred treatment drug for autoimmune diseases such as rheumatoid arthritis, with complicated chemical composition and anti-inflammatory, antitumor, immune regulation, and anti-reproductive function, is one of the hot natural medicines both at home and abroad. However, liver damage caused by T. wilfordii is reported frequently, which greatly limits its clinical application. In this paper, we collect and summarize the researches on the hepatotoxicity and compatibility of T. wilfordii in recent years based on the "detoxicity compatibility" theory of Chinese medicine compatibility. Meanwhile, we propose the principle of prescription to reduce the hepatotoxicity of T. wilfordii by compatibility mechanism, with a view to improve the security of the clinical application of T. wilfordii.
