Preparation of polysaccharides, alkaloids, and polyphenols from fresh Portulaca oleracea and their anti-diabetic effects
10.7501/j.issn.0253-2670.2014.18.019
- Author:
Zhi-Yin ZHENG
1
Author Information
1. Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Alkaloids;
Fresh Portulaca oleracea L.;
Hypoglycemic;
Polyphenols;
Polysaccharides
- From:
Chinese Traditional and Herbal Drugs
2014;45(18):2673-2677
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To prepare polysaccharides, alkaloids, and polyphenols from fresh Portulaca oleracea and study their hypoglycemic effects. Methods: The suitable macroporous resin and adequate separation and purification technology were selected to prepare polysaccharides, alkaloids, and polyphenols from fresh P. oleracea; Then their hypoglycemic effects were studied by analyzing fasting blood serum, insulin, and MDA and SOD from STZ induced diabetic mice. Results: All these three compositions can low fasting blood serum of diabetic mice. What's more, polysaccharides and polyphenols can obviously improve the content of SOD and degrade the content of MDA, while alkaloids can promote pancreatic β echylosis. Conclusion: Polysaccharides, alkaloids, and polyphenols from fresh P. oleracea possess anti-diabetic effects, and the integral administration of the three compositions has better hypoglycemic effect.
