Research progress on pharmacokinetics of cardiac glycosides
10.7501/j.issn.0253-2670.2014.23.022
- Author:
Yu-Meng JIA
1
Author Information
1. Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University
- Publication Type:Journal Article
- Keywords:
Antitumor;
Arythmia;
Cardiac glycosides;
Chronic heart failure;
Pharmacokinetics
- From:
Chinese Traditional and Herbal Drugs
2014;45(23):3472-3477
- CountryChina
- Language:Chinese
-
Abstract:
Cardiac glycosides are proven to be effective in the clinical treatment for chronic heart failure and certain types of arrhythmia, especially for antitumor treatment. This paper focused on the research progress on pharmacokinetics of cardiac glycosides in recent years, elucidated the behaviors of absorption, distribution, metabolism, and excretion in vivo and in vitro, and summarized the metabolism of this kind of drug, aiming to provide an evidence for new drug research as well as a reference for the clinical safe use of these drugs.
