Effects of Xueshuantong injection on platelet aggregation in rabbits in vitro
10.7501/j.issn.0253-2670.2014.18.018
- Author:
Yan-Yan WANG
1
Author Information
1. Tianjin University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Arachidonic acid;
Platelet aggregation;
Platelet-activating factor;
Total saponins of Panax notoginseng;
Xueshuantong injection
- From:
Chinese Traditional and Herbal Drugs
2014;45(18):2669-2672
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effects of Xueshuantong injection (lyophilized, main component of Panax Notoginsenosidum, total content of 95%) on platelet aggregation induced by adenosine diphosphate (ADP), arachidonic acid (AA), and platelet-activating factor (PAF) in rabbits. Methods: Using the Born method, the platelet aggregation induced by ADP, AA, and PAF was detected. Results: Compared with the control group, Xueshuantong injection (7.2 and 14.4 mg/mL) could significantly inhibit the platelet aggregation rate induced by ADP, AA, and PAF (P < 0.01), Xueshuantong injection (3.6 mg/mL) could significantly inhibit the platelet aggregation rate induced by ADP (P < 0.01). Conclusion: Xueshuantong injection could inhibit the in vitro platelet aggregation of rabbits.
