Chemical constituents in root barks of Lycium chinense
10.7501/j.issn.0253-2670.2014.15.004
- Author:
Ling-Jie MENG
1
Author Information
1. Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University
- Publication Type:Journal Article
- Keywords:
Apigenin;
Ferulic acid;
N-trans-coumaroyltyramine;
N-trans-feruloyltyramine;
Root barks of Lycium chinense Mill.
- From:
Chinese Traditional and Herbal Drugs
2014;45(15):2139-2142
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents from the root barks of Lycium chinense. Methods: The chemical constituents of EtOAc fraction from 95% ethanol extract of L. chinense were isolated and purified by chromatography on silica gel, Sephadex LH-20, and ODS. Their chemical structures were identified on the basis of physicochemical properties and spectroscopic data. Results: Twelve compounds were isolated and identified as N-trans-coumaroyltyramine (1), N-trans-feruloyltyramine (2), dihydro-N-caffeoyltyramine (3), apigenin (4), ferulic acid (5), p-hydroxycinnamic acid (6), 3-hydroxy-1-(4-hydroxyphenyl)-1-propanone (7), 3, 4-dihydroxybenzenepropionic acid (8), 3, 4-dihydroxybenzenepropionic acid methyl ester (9), p-hydroxy-benzoic acid (10), 4-methoxy salicylic acid (11), and nicotinic acid (12). Conclusion: Compounds 8 and 9 are two new natural products, and compounds 1, 6, 11, and 12 are obtained from this plant for the first time.
