Flavane constituents from branch of Celastrus hindsii
10.7501/j.issn.0253-2670.2014.15.002
- Author:
Xian-Qing HU
1
Author Information
1. School of Pharmacy, East China University of Science and Technology
- Publication Type:Journal Article
- Keywords:
(2S)-7, 3'-dimethoxy-4'-hydroxyflavan;
(2S)-7, 3'-dimethoxy-6, 4'-dihydroxyflavan;
6, 7, 3'-trimethoxy-4'-hydroxyflavan;
6, 7-dimethoxy-3', 4'-dihydroxyflavan;
Cleastrus hindsii Benth.;
Enantiomers;
Hindsiflavane A;
Hindsiflavane B;
Hindsiflavane C
- From:
Chinese Traditional and Herbal Drugs
2014;45(15):2132-2135
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents in the branch of Cleastrus hindsii from Yunnan province. Methods: The compounds were separated and purified by column chromatography with silica gel, RP C18, Sephadex LH-20 columns, and preparative TLC. Their structures were elucidated by the basis of spectroscopic methods and chemical evidences. Results: Four flavanes were isolated from 80% ethanol extract from the branch of C. hindsii and identified as (2S)-7, 3'-dimethoxy-6, 4'-dihydroxyflavan (1), 6, 7, 3'-trimethoxy-4'-hydroxyflavan (2), 6, 7-dimethoxy-3', 4'-dihydroxyflavan (3), and (2S)-7, 3'-dimethoxy-4'-hydroxyflavan (4), respectively. Conclusion: Compounds 1-3 are new flavanes with X-ray data, named hindsiflavane A-C, and compounds 2 and 3 are a couple of enantiomers, respectively. Compound 4 is isolated from this plant for the first time.
