Emprovement of Rhodiola rosea on intestinal immune function of Drosophila melanogaster
- Author:
Zhan-Guang ZUO
1
Author Information
1. College of Life Science, Northeast Forestry University
- Publication Type:Journal Article
- Keywords:
Drosophila melanogaster Meigen;
Intestinal epithelium cell;
Intestinal immunity;
Rhodiola rosea L.;
Survival rate
- From:
Chinese Traditional and Herbal Drugs
2014;45(5):691-694
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effect of Rhodiola rosea extracts on intestinal immune function of Drosophila melanogaster. Methods: D. melanogaster was treated by SDS and fungal biological solution with or without R. rosea extracts, and the effect of R. rosea extracts on the survival rate of D. melanogaster, intestinal epithelium cell death, relative contents of reactive oxygen species (ROS) in intestinal epithelium cells, and intestinal morphology changes were analyzed. Results: R. rosea extracts could significantly improve the survival rate of SDS and fungus (Beauveria bassiana)-infected D. melanogaster (P < 0.05), reduce the intestinal epithelial cell death and the level of intestinal ROS levels, and protect and maintain the intestinal morphology. Conclusion: R. rosea extracts could significantly improve the intestinal immune function of D. melanogaster with the amelioration and protection of intestinal immunologic function injury induced by fungi and SDS.
