Chemical constituents in root bark of Changium smyrnioides
10.7501/j.issn.0253-2670.2014.12.003
- Author:
Gang-Gang BAI
1
Author Information
1. College of Pharmacy, Nanjing University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Alloimperatorin;
Aurantiamide acetate;
Bergapten;
Caffeic acid;
Changium smyrnioides Wolff;
Isopimpinellin;
Psoralen
- From:
Chinese Traditional and Herbal Drugs
2014;45(12):1673-1676
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents from the root bark of Changium smyrnioides. Methods: Compounds were isolated by various kinds of column chromatographies on silica gel, Sephadex LH-20, and recycling preparative HPLC from the ethanol extract in the root bark of C. smyrnioides, and their structures were elucidated by the physicochemical characteristics and spectral analyses. Results: Fifteen chemical constituents were obtained and identified as imperatorin (1), phellopterin (2), xanthotoxol (3), 5-hydroxy-8-methoxy-psoralen (4), vanillic acid (5), alloimperatorin (6), psoralen (7), bergapten (8), 8-O-β-D-glucopyranosyl- 5-methoxylpsoralen (9), isopimpinellin (10), caffeic acid (11), aurantiamide acetate (12), vaginatin (13), β-sitosterol (14), and succinic acid (15). Conclusion: Compounds 6-13 are isolated from the plants in Changium Wolff for the first time.
