Study on immunomodulatory activity of root and rhizome of Rosa laevigata from different habitats
10.7501/j.issn.0253-2670.2014.13.018
- Author:
Hai-Yan PENG
1
Author Information
1. Guilin Sanjin Pharmaceutical Co., Ltd.
- Publication Type:Journal Article
- Keywords:
Cellular immunity;
Humoral immunity;
Immunomodulation;
Non-specific immunity;
Rhizomes;
Roots;
Rosa Laevigata Radix
- From:
Chinese Traditional and Herbal Drugs
2014;45(13):1903-1906
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the immunomodulatory activity of the roots and rhizomes in Rosa laevigata (Rosa Laevigata Radix) in Guangxi, Yunnan, and Guizhou provinces. Methods: The effects of cellular immunity, humoral inmunity, and non-specific immunity were investigated on delayed-type hypersensitivity, serum hemolysin antibody, and carbon clearance of mice, respectively. Results: Rosa Laevigata Radix could inhibit the delayed-type hypersensitivity and serum hemolysin antibody in mice, but had no effect on carbon clearance. All the roots and rhizomes of R. laevigata from different habitats had no statistically significant difference on immunomodulatory activity. Conclusion: The roots and rhizomes of R. laevigata from different habitats have the similar immunosuppressive activity.
