Optimization of extraction technology for Asteris Radix et Rhizoma in Zibai Zhisou Capsules with orthogonal test
10.7501/j.issn.0253-2670.2014.14.013
- Author:
Hai-Ning WANG
1
Author Information
1. Guizhou Institute for Food and Drug Control
- Publication Type:Journal Article
- Keywords:
Asteris Radix et Rhizoma;
Astersaponin;
Extraction technology;
Orthogonal test;
Shionone;
Zibai Zhisou Capsules
- From:
Chinese Traditional and Herbal Drugs
2014;45(14):2027-2029
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To optimize the extraction technology of Asteris Radix et Rhizoma in Zibai Zhisou Capsules. Methods: Orthogonal test was carried out. The influences of concentration of solvent, the dosage of solvent, duration of extraction, and frequency of extraction on extraction results were investigated by using the content of shionons as index. Results: The optimal extraction technique was to extract pueraria in 80% alcohol with 8 times the weight of herbal medicine for 3 times, with 60 min once. Conclusion: High yield of extractum and high content of shionon are obtained with the present technology. The results with better repeatability are stable, which can provide the reference for the production of Zibai Zhisou Capsules.