Chemical constituents of Evodia lepta in Pattra medicine
10.7501/j.issn.0253-2670.2014.14.001
- Author:
Shu-Juan YANG
1
Author Information
1. Liangfang Research and Development Center of Pattra Medicine of Yunnan
- Publication Type:Journal Article
- Keywords:
2, 4, 6-trihydroxyacetophenone;
2, 4, 6-trihydroxyacetophenone-3, 5-di-C-β-D-glucoside;
Evodia lepta (Spreng.) Merr.;
Leptabiside A;
Leptabiside B;
Leptabiside C;
Pattra medicine
- From:
Chinese Traditional and Herbal Drugs
2014;45(14):1971-1975
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents of Pattra medicine Evodia lepta from Xishuangbanna of Yunnan province, China. Methods: The chemical constituents were isolated and purified by chromatographic techniques, and identified by NMR, MS, and other spectral methods with chemical hydrolysis. Results: In 95% ethanol extract from the leaves of E. lepta, four compounds were isolated and their structures were identified as 2, 4, 6-trihydroxyacetophenone-3, 5-di-C-β-D-glucoside (1), 2, 4, 6-trihydroxy- acetophenone-3, 5-di-C-β (6'-O-E-p-coumaroyl)-D-glucoside (2), 2, 4, 6-trihydroxyacetophenone-3, 5-di-C-β(6'-O-Z-p-coumaroyl)- D-glucoside (3), and 2, 4, 6-trihydroxyacetophenone-3, 5-di-C-β (6'-O-E-cinnamoyl)-D-glucoside (4), respectively. Conclusion: Compounds 2-4 are new compounds named leptabiside A, B, and C, respectively. Compound 1 is obtained from domestic E. lepta for the first time.
