Preparation technology of isochlorogenic acids A, B, and C
10.7501/j.issn.0253-2670.2015.03.012
- Author:
Fu-Yong NI
1
Author Information
1. Jiangsu Kanion Pharmaceutical Co. Ltd.
- Publication Type:Journal Article
- Keywords:
D-101 macroporous resin;
Isochlorogenic acid A;
Isochlorogenic acid B;
Isochlorogenic acid C;
Lonicerae Flos;
Medium-low-pressure preparative chromatography
- From:
Chinese Traditional and Herbal Drugs
2015;46(3):369-373
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish a method for separation of isochlorogenic acids A, B, and C from Lonicerae Flos. Methods: Isochlorogenic acids A, B, and C in Lonicerae Flos were isolated and purified by macroporous resin and medium-low-pressure preparative chromatography. Their structures were identified on the basis of the spectral data and physicochemical property. Results: The contents of prepared isochlorogenic acids A, B and C were 98.7%, 99.2%, and 97.6%, respectively. Conclusion: This method is economic, simple, rapid, and effective for the preparation of isochlorogenic acids A, B, and C with high purity.
