Primary Malignant Melanoma of the Esophagus: A case report.
- Author:
Lee So MAENG
;
Kyoung Mee KIM
;
Eun Jung LEE
;
Anhi LEE
;
Sang In SHIM
- Publication Type:Case Report
- Keywords:
Melanoma;
Esophagus;
Melanosis
- MeSH:
Adult;
Cytoplasm;
Deglutition Disorders;
Epithelioid Cells;
Esophagus*;
Female;
Humans;
Melanoma*;
Melanosis;
Mucous Membrane;
Nuclear Family;
Pigmentation;
S100 Proteins;
Stomach;
Triacetoneamine-N-Oxyl
- From:Korean Journal of Pathology
1998;32(9):694-696
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This report presents an unusual case of primary malignant melanoma in the midesophagus. The patient was a 36-year-old woman presenting with dysphagia and odynophagia. The resected esophagus and proximal stomach showed a dark purple large polypoid mass, measuring 6.0 3.3 2.0 cm, with a diffuse tan pigmentation of surrounding mucosa in the mid-esophagus and two small daughter nodules, up to 1.2 0.3 cm, in the lower esophagus near the gastro-esophageal junction. A microscopic examination revealed a malignant melanoma of epithelioid cell type confined to mucosa and submucosa with a diffuse melanosis. Cytoplasmic immunoreactivity for HMB 45 and S-100 protein were noted. An electron microscopic examination revealed large, loosely cohesive variable shaped cells with a few cytoplasmic premelanosomes.
