Well-Differentiated Papillary Mesothelioma of the Peritoneum: A case report .
- Author:
Yi Kyeong CHUN
;
Yee Jeong KIM
;
Sung Ran HONG
- Publication Type:Case Report
- Keywords:
Well differentiated papillary mesothelioma;
Peritoneum;
Mesothelioma
- MeSH:
Carcinoembryonic Antigen;
Desmosomes;
Hysterectomy;
Keratins;
Mesothelioma*;
Microvilli;
Peritoneum*
- From:Korean Journal of Pathology
1998;32(9):697-699
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Well-differentiated papillary mesothelioma (WDPM) of the peritoneum is considered to be a distinct subtype of peritoneal mesothelioma and has mostly behaved in a benign fashion. We report a case of WDPM in a 48-year-old-woman. It was incidentally found during a hysterectomy for a uterine cervical carcinoma. Grossly, the tumor was composed of multiple peritoneal nodules, measuring up to 2 cm. Microscopically, the nodules showed well-developed papillae lined by a single layer of cuboidal mesothelial cells. Immunohistochemical staining revealed a positive reaction for cytokeratin and a negative reacion for carcinoembryonic antigen and Leu-M1. Ultrastructurally, the tumor cells showed numerous long, slender microvilli and desmosomes.