Comparison on chemical components and hypoglycemic activities between two closely-related Chinese materia medica
10.7501/j.issn.0253-2670.2015.16.025
- Author:
Hui-Yuan CONG
1
Author Information
1. Tianjin University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Agrimoniae Herba;
Biosynthesis pathway;
Hypoglycemic;
Pharmaphylogeny;
Potentillae Discoloris cum Radice Herba
- From:
Chinese Traditional and Herbal Drugs
2015;46(16):2484-2491
- CountryChina
- Language:Chinese
-
Abstract:
Potentillae Discoloris cum Radice Herba and Agrimoniae Herba are closely-related medicinal plants in Rosaceae with specific hypoglycemic activities and applied as Chinese materia medica in clinical practice for the treatment of diabetes. Based upon pharmaphylogeny theories, the biosynthetic pathways of the principal active components of the above two Chinese herbs were summarized, and the commonness and differences of the active components were compared further and the correlation between material basis and curative effects was summarized as well. The results indicated that the common biosynthetic pathways of the two Chinese herbs accounted for 60%; The common components of tiliroside and quercetin, etc. as well as the differentiated components of potengriffioside A and rosolic acid, etc. are also the active components; The differences of the characteristic components and their contents may lead to the differences of functions and modes of action between the two Chinese herbs.
