Chromatography fingerprint of Schisandra chinensis Chewable Tablets by HPLC-DAD
10.7501/j.issn.0253-2670.2015.16.012
- Author:
Min YU
1
Author Information
1. Jinlin Academy of Traditional Chinese Medicine, Institute of Plant Chemistry
- Publication Type:Journal Article
- Keywords:
3, 4-dihydroxyhenzaldehyde;
Buddleoside;
Chromatography fingerprint;
Cryptotanshinone;
HPLC-DAD;
Luteoloside;
Salvianic acid A sodium;
Salvianolic acid B;
Schisandra chinensis Chewable Tablets;
Schisandrin;
Schisandrin B;
Schisandrin C;
Schisandrol B;
Schisantherin A;
Tanshinone IIA
- From:
Chinese Traditional and Herbal Drugs
2015;46(16):2413-2416
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish the chromatography fingerprint of Schisandra chinensis Chewable Tablets (SCCT) with HPLC-DAD and to evaluate SCCT from 10 different batches. Methods: Luna C18 column (250 mm×4.6 mm, 5 μm) was used, mobile phase was acetonitrile-0.05% phosphate, flow speed was 1.0 mL/min, temperature of column was set at 35℃, detected wavelength was at 220 nm, and injection volume was 20 μL. Results: The chromatography fingerprint of SCCT from 10 different batches was established. In the chromatography fingerprint with HPLC-DAD of SCCT, 39 common peaks were demarcated and the similarities of SCCT were between 0.914-0.999. Schizandrin, schisandrol B, schisantherin A, schisandrin B, schisandrin C, salvianic acid A sodium, salvianolic acid B, cryptotanshinone, tanshinone IIA, 3, 4-dihydroxyhenzaldehyde, luteoloside, and buddleoside were identified. Conclusion: The method is accurate, reliable and with good reproducibility, and can be used as the evidence for the quality evaluation of SCCT.
