Cyclodipeptides from medicinal insect Blaps rynchopetera
10.7501/j.issn.0253-2670.2015.16.007
- Author:
Qing LUO
1
Author Information
1. Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, Dali University
- Publication Type:Journal Article
- Keywords:
Blaps rynchopetera Fairmaire;
Cyclo (Ile-Pro);
Cyclo (Leu-Pro);
Cyclo (Ser-Pro);
Cyclo (Val-Pro);
Medical insects
- From:
Chinese Traditional and Herbal Drugs
2015;46(16):2381-2384
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents of Blaps rynchopetera. Methods: Compounds were isolated and purified on silica gel, Sephadex LH20, ODS, and D101 column chromtography. The structures were elucidated on the basis of NMR spectral data and HR-ESI-MS. Results: Ten cyclodipeptides were isolated from the n-butyl extract fraction of B. rynchopetera, and their structures were determined as cyclo (Leu-Pro) (1), cyclo (Val-Pro) (2), cyclo (Ile-Pro) (3), cyclo (Ser-Pro) (4), cyclo (Tyr-Pro) (5), cyclo (Val-Ile) (6), cyclo (Val-Leu) (7), cyclo (Val-Tyr) (8), cyclo (Ile-Tyr) (9), and cyclo (Phe-Tyr) (10). Conclusion: All the 10 compounds are isolated from B. rynchopetera for the first time.
