Research progress in hypoglycemic effect and mechanism of heat-clearing and detoxifying Chinese materia medica
10.7501/j.issn.0253-2670.2015.17.024
- Author:
Jin-Ni HONG
1
Author Information
1. Integrated Laboratory of Traditional Chinese Medicine and Western Medicine, First Hospital, Peking University
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Heat toxin;
Heat-clearing and detoxifying;
Hypoglycemic effect;
Mechanism
- From:
Chinese Traditional and Herbal Drugs
2015;46(17):2656-2661
- CountryChina
- Language:Chinese
-
Abstract:
Heat-toxin stagnation is regarded to be an important pathologic mechanism of diabetes mellitus (DM) in terms of traditional Chinese medicine. Treating DM with heat-clearing and detoxifying principle on the basis of syndrome differentiation proves to be effective. Heat-clearing and detoxifying Chinese materia medica can decrease blood sugar by protecting islet β-cell, improving insulin resistance, regulating glucose metabolism and lipid metabolism, regulating GLP-1, inflammatory cytokines, and intestinal microflora.