Research progress in structure-activity relationship of flavoniods
10.7501/j.issn.0253-2670.2015.21.025
- Author:
Xue-Wei ZHAO
1
Author Information
1. Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University
- Publication Type:Journal Article
- Keywords:
Flavonoids;
Natural products;
Skeleton structure;
Structure classification;
Structure-activity relationship
- From:
Chinese Traditional and Herbal Drugs
2015;46(21):3264-3271
- CountryChina
- Language:Chinese
-
Abstract:
Flavonoids are a large type of compounds in natural products, and they have varied structure subtypes, with the basic structural framework of C6-C3-C6. Flavonoids are widely distributed in nature, from fruits and vegetables to Chinese materia medica, and they have also been found to have a wide variety of biological activities, so they have always been the hot spot of the drug development. Flavonoids as lead compounds or directly developed drugs have already been widely used. Lots of studies have been reported about structure-activity relationship of flavonoids. This review summarized research progress of structure-activity relationship of flavonoids in recent years.