Research progress on local pharmacokinetics of novel drug delivery system of Chinese materia medica
10.7501/j.issn.0253-2670.2015.21.024
- Author:
Hong-Bing ZHANG
1
Author Information
1. Tianjin University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Chinese materia medica;
Integrative pharmacokinetics;
Local pharmacokinetics;
Novel drug delivery system;
Targeted drug delivery system
- From:
Chinese Traditional and Herbal Drugs
2015;46(21):3258-3263
- CountryChina
- Language:Chinese
-
Abstract:
With rapid development of modern science and technology, much progress has been made in novel drug delivery system of Chinese materia medica (CMM), combined with new polymer materials and multidisciplinary knowledge. Compared with the traditional preparation, novel drug delivery system in drug distribution in vivo presented high selectivity. In addition, there was no clear correlation between drug concentration in blood and efficacy. Pharmacokinetic process in local target in effect should therefore be systematically investigated. In this article, the author reviewed the means and technology of local pharmacokinetic study on novel drug delivery system for CMM, as well as progress made, and further discussed the developmental issues and challenges.
