Chemical constituents of Sabia parviflora
10.7501/j.issn.0253-2670.2015.21.003
- Author:
Yan CHEN
1
Author Information
1. Institute of Chemistry and Chemical Engineering in Guizhou University
- Publication Type:Journal Article
- Keywords:
3-oxooleanolic acid;
Alkaloids;
Methyl betulinate;
Mominine;
Pentacyclic triterpenes;
Sabia parviflora Wall. ex Roxb.
- From:
Chinese Traditional and Herbal Drugs
2015;46(21):3146-3150
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents from the stems and leaves of Sabia parviflora. Methods: Column chromatographies over silica gel, Sephadex LH-20, reverse phase C18, MCI, and semi-preparative HPLC were used repeatedly for separation and purification of chemical constituents, and their structures were identified by NMR and MS spectra data with those reported in literature. Results: Fourteen compounds were obtained from the petroleum ether extract of S. parviflora, and identified as β-sitosterol (1), mominine (2), (20S)-3-oxo-20-hydroxytaraxastane (3), fluoren-9-one (4), N-formyldehydroanonain (5), betulinic acid (6), dehydroformouregine (7), palmitic acid (8), 20-hydroxy-lupan-3-one (9), 3-oxooleanolic acid (10), erythrodiol (11), methyl betulinate (12), N-formyl-annonain (Z) (13), and N-formyl-O-methylisopiline (14). Conclusion: Among the 14 compounds, there are seven pentacyclic triterpenes, four alkaloids, and three other compounds; compounds 3-10 and 12-14 are isolated from this plant and the plants of Sabia Colebr. for the first time, and the 13C-NMR spectral assignments of compounds 5, 7, and 14 are reported for the first time.
