20(S)-Ginsenoside-Rf2, a novel triterpenoid saponin from stems and leaves of Panax ginseng
10.7501/j.issn.0253-2670.2015.21.002
- Author:
Xiu-Wei YANG
1
Author Information
1. Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University
- Publication Type:Journal Article
- Keywords:
20(R)-ginsenoside Rf2;
20(S)-ginsenoside Rf2;
20(S)-ginsenoside Rh1;
Ginsenoside;
Rare ginsenoside;
Stems and leaves of Panax ginseng
- From:
Chinese Traditional and Herbal Drugs
2015;46(21):3137-3145
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents of saponins in the stems and leaves of Panax ginseng. Methods: The chemical constituents were isolated and purified by various chromatographic methods, and the chemical structures were identified by NMR and MS data analyses. Results: A total of 39 compounds were isolated and identified. Among them, 17 compounds were determined as ginsenoside Re (1), 20(S)-ginsenoside Rh1 (2), 20(R)-ginsenoside Rh1 (3), ginsenoside Rh5 (4), 20(E)-ginsenoside F4 (5), ginsenoside F2 (6), 20(S)-ginsenoside Rg3 (7), 20(R)-ginsenoside Rg3 (8), 20(S)-ginsenoside Rf2 (9), 20(R)-ginsenoside Rf2 (10), 20(S)- protopanaxadiol (11), 20(R)-protopanaxadiol (12), 20(S)-ginsenoside Rh2 (13), 20(R)-ginsenoside Rh2 (14), 20(S)-protopanaxatriol (15), 20(R)-protopanaxatriol (16), and ginsenoside Rd (17). Conclusion: Compound 9 is a new saponin. Compounds 2-10, 13, and 14 are rare ginsenosides.
