Research progress on metabolism and interaction of Salvia miltiorrhiza based on cytochrome P450s
10.7501/j.issn.0253-2670.2016.01.026
- Author:
Fei-Yan ZHANG
1
Author Information
1. Pharmacy College, Southwest University
- Publication Type:Journal Article
- Keywords:
Cytochrome P450;
Drug metabolism;
Extract;
Formula;
Individual;
Salvia miltiorrhiza Bunge
- From:
Chinese Traditional and Herbal Drugs
2016;47(1):175-182
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the Chinese medicine Salvia miltiorrhiza has been widely used in cardiovascular and cerebrovascular diseases. So, the interaction between S. miltiorrhiza and cytochrome P450s are focused increasingly. This review summarized the research progress on the cytochrome P450s-based metabolism and interaction of S. miltiorrhiza, including its extracts, major individuals, and S. miltiorrhiza-based formulas. It systematically summarized the information which were useful for the further applications and researches on S. miltiorrhiza and its active components.