Preparation of molecular imprinted polymers for solid-phase extraction of L-tetrahydropalmatine
10.7501/j.issn.0253-2670.2016.01.011
- Author:
Jun-Fang ZHU
1
Author Information
1. Guangdong Food and Drug Vocational College
- Publication Type:Journal Article
- Keywords:
Corydaline;
Ehtylene glycol dimethacrylate;
L-tetrahydropalmatine;
Methyl acrylic acid;
Molecular imprinting technique;
Molecularly imprinted polymer;
Solid-phase extraction
- From:
Chinese Traditional and Herbal Drugs
2016;47(1):72-75
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To prepare the molecularly imprinted polymer (MIPs) of L-tetrahydropalmatine (L-THP) by the molecular imprinting technique and study on solid-phase extraction. Methods: Using L-THP as template, methyl acrylic acid (MAA) as functional monmer, and ehtylene glycol dimethacrylate (EDMA) as a cross-linking agent to prepare the L-THP-MIPs. A test was conducted to investigate the selectivity and the specificity of solid-phase extraction. Results: The experiment showed that the MIPs had the specific adsorption to L-THP, but did not have the specific adsorption to corydaline the structural analogue with L-THP. Conclusion: The L-THP-MIPs have a good selectivity and the specificity of L-THP.
