Chemical constituents from leaves of Perilla frutescens
10.7501/j.issn.0253-2670.2016.01.005
- Author:
Li-Na HUO
1
Author Information
1. School of Pharmacy, Qingdao University
- Publication Type:Journal Article
- Keywords:
Esculetin;
Lamiaceae;
Perilla frutescens (L.) Britt.;
Rosmarinic acid;
Scutellarin
- From:
Chinese Traditional and Herbal Drugs
2016;47(1):26-31
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents from the aqueous extract of leaves of Perilla frutescens. Methods: The compounds were isolated and purified by chromatography on macroporous resin, silica gel, ODS, and preparative HPLC. Their structures were elucidated on the basis of chemical and spectroscopic methods, including MS, 1D and 2D NMR spectral techniques. Results: Seventeen compounds were isolated from the aqueous extract of leaves of P. frutescens, and were identified as (+)- isololiolide (1), dehydrovomifoliol (2), (-)-loliolide (3), scutellarin (4), p-hydroxybenzaldehyde (5), p-hydroxyacetophenone (6), 3-formylindole (7), trans-p-hydroxycinnamic acid (8), apigenin (9), luteolin (10), esculetin (11), caffeic acid (12), rosmarinic acid (13), methyl rosmarinate (14), sericoside (15), caffeic acid vinyl ester (16), and negletein (17). Conclusion: Compounds 1-2, 6-8, and 15 are firstly isolated from the plants of Perilla Linn.
