Chemical constituents of non-alkaloids from Huperzia serrata
10.7501/j.issn.0253-2670.2016.01.003
- Author:
Kai-Kai ZHENG
1
Author Information
1. Department of Phytochemistry, Shanghai University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
1-dibenzofuranol;
Dibenzofuranol;
Huperzia Bemh;
Huperzia serrata (Thunb.) Trev.;
Non-alkaloids;
Seratenediol-3,21-diacetate;
Serratcoumarate;
Serratene-type triterpenoids
- From:
Chinese Traditional and Herbal Drugs
2016;47(1):15-20
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the non-alkaloids in Huperzia serrata. Methods: The constituents were mainly isolated and purified by means of silica gel, RP18, and Sephadex LH-20 column chromatographies. The structures were identified based on analyses of the spectral data of NMR and MS. Results: Totally 11 constituents were obtained from dichloromethane fraction of the plant and they were 3β-hydroxyserrat-14-en-21β-yl-p-dihydrocoumarate (1), seratenediol-3,21-diacetate (2), seratenediol-3-acetate (3), 21-epi-serratenediol-3-acetate (4), 3α,21β,24-trihydroxyserrat-14-en (5), 21-epi-serratenediol (6), serratenediol (7), 3α,21β-dihydroxy- serrat-14-en-16-one (8), 3β,21β,24-trihydroxyserrat-14-en (9), 3α,21β,24-trihydroxyserrat-14-en-16-one (10), and 1-dibenzofuranol (11). Conclusion: Compounds 1-10 are serratene-type triterpenoids and compound 11 is a dibenzofuranol. Compounds 1 is a new compound named as serratcoumarate and compounds 2 and 11 are isolated from the plant for the first time.
