Flavonoids from roots and rhizomes of Rhodiola crenulata
10.7501/j.issn.0253-2670.2016.02.006
- Author:
Fu-Yong NI
1
Author Information
1. Jiangsu Kanion Pharmaceutical Co., Ltd.
- Publication Type:Journal Article
- Keywords:
3,5,7,3'-tetrahydroxyflavone;
3,5-dihydroxy-3',4',7-trimethoxyflavone;
5,4'-dihydroxy-7,3'-dimethoxyflavone;
Quercetin-3-O-α-L-rhamnopyranoside;
Rhodiola crenulata (HK. f. et Thoms.) H. Ohba
- From:
Chinese Traditional and Herbal Drugs
2016;47(2):214-218
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents from the roots and rhizomes of Rhodiola crenulata. Methods: The chemical constituents were isolated by repeated silica gel chromatography and medium pressure column chromatography. Their structures were identified by various spectroscopic data including ESI-MS, 1H-NMR, and 13C-NMR data. Results: Fourteen compounds were isolated from the ethyl acetate fractions of R. crenulata including 3,5-dihydroxy-3',4',7-trimethoxyflavone (1), 3,5,7,3'-tetrahydroxyflavone (2), 5,4'-dihydroxy-7,3'-dimethoxyflavone (3), kaemnpferol (4), kaemnpferol-3-O-β-D-glucopyranoside (5), kaemnpferol-3-O-α-L- rhamnopyranoside (6), tricin (7), tricin-7-O-β-D-glucopyranoside (8), quercetin (9), quercetin-3-O-β-D-glucopyranoside (10), quercetin-3-O-α-L-rhamnopyranoside (11), herbacetin-3-O-β-D-glucopyranoside (12), herbacetin-7-O-β-D-glucopyranoside (13), and herbacetin-7-O-α-L-rhamnoside (14). Conclusion: Compounds 1-3 are isolated from the plants in Rhodiola L. for the first time, compounds 5-6, 8, 10-13 are obtained from this plant for the first time.
