Study on chemical constituents from Gnaphalium affine and their anti-oxidative activities
10.7501/j.issn.0253-2670.2016.04.004
- Author:
Li-Ming BAI
1
Author Information
1. Institute of Chemistry and Chemistry Engineering, Qiqihar University
- Publication Type:Journal Article
- Keywords:
Apigenin;
Chrysin;
Gnaphalium affine D. Don;
Luteolin;
Wogonin;
α-amyrin acetate
- From:
Chinese Traditional and Herbal Drugs
2016;47(4):549-553
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents from Gnaphalium affine and their anti-oxidative activities. Methods: Chemical constituents were isolated by column chromatography and semi-prepared HPLC, the structures were elucidated by spectral data and physicochemical properties. DPPH free radical scavenging activities of compounds 1,3-11, and 16 were determined. Results: Seventeen compounds were isolated and respectively identified as apigenin (1), dihydroapigenin (2), luteolin (3), chrysin (4), wogonin (5), stimasterol (6), β-sitosterol (7), ursolic acid (8), oleanolic acid (9), 19α-hydroxyl-oleanolic acid (10), 2α, 3α, 19α-trihydroxy-28-norurs-12ene (11), α-amyrin acetate (12), β-amyrin acetate (13), patriscabratine (14), aurantiamide acetate (15), 4'-hydroxydehydrokawain (16), and isovanillin (17). Compounds 1 and 3-5 had significant anti-oxidative activities. Conclusion: Compounds 2,4,5,11-15, and 17 are isolated from G. affine for the frist time.
