Chemical constituents in stems of Ilex cornuta
10.7501/j.issn.0253-2670.2016.06.006
- Author:
Chen-Mei MAO
1
Author Information
1. Children's Hospital of Soochow University
- Publication Type:Journal Article
- Keywords:
3,4,5-tri-O-caffeoyl quinic acid methyl ester;
3,4,5-tricaffeoylquinic acid;
3,4-di-O-caffeoyl quinicacid methyl ester;
3,5-di-O-caffeoyl quinicacid methyl ester;
3,5-dimethoxy-4-hydroxybenzaldehyde;
4,5-di-O-caffeoyl quinic acid methyl ester;
Anti-oxidant activity;
Ilex cornuta Lindl. et Paxt.;
Isochlorogenic acid B
- From:
Chinese Traditional and Herbal Drugs
2016;47(6):891-896
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents in the stems of Ilex cornuta and the ability of scavenging free radicals of compounds 1-9. Methods: The compounds were isolated and purified by silica gel, medium pressure column chromatography, and semi-preparative liquid chromatography, and their structures were elucidated by chemical properties and spectroscopic analyses. The antifreeradical efficiency of compounds 1-9 was evaluated by DPPH radical scavenging assay. Results: Fifteen compounds were isolated and their structures were identified as isochlorogenic acid B (1), 3,4,5-tricaffeoylquinic acid (2), 4,5-di-O-caffeoyl quinic acid methyl ester (3), 3,4-di-O-caffeoyl quinicacid methyl ester (4), 3,5-di-O-caffeoyl quinicacid methyl ester (5), 3,4,5-tri-O-caffeoyl quinic acid methyl ester (6), 3,5-dimethoxy-4-hydroxybenzaldehyde (7), ethyl gallate (8), dihydrosyringenin (9), 2,6-dimethoxy-1,4-benzoquinone (10), arctigenin (11), 1-O-(vanillic acid)-6-O-(3″, 5″-dimethoxy-galloyl)-β-D-glycoside (12), (+)-1-hydroxypinoresinol-1-O-β-D-glucopyranoside (13), (+)-(7S,8S)-syringylglycerol 8-O-β-D-glucopyranoside (14), and schaftoside (15). Compounds 1-7 had good antifreeradical efficiency. Conclusion: Compounds 6,8-10,14, and 15 are obtained from the plants of Ilex L. the first time, and compounds 2,7,11, and 12 are obtained from this plant for the first time. Compounds 1-6 have good antifreeradical efficiency.
