Chemical constituents from rhizomes of Curcuma longa
10.7501/j.issn.0253-2670.2016.07.002
- Author:
Yu-Han CUI
1
Author Information
1. Department of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University
- Publication Type:Journal Article
- Keywords:
5-hydroxyl-bisabolon-9-one;
Curcuma longa L.;
Curcumin;
Isodemethoxyl cyclocurcumin;
Vanillin
- From:
Chinese Traditional and Herbal Drugs
2016;47(7):1074-1078
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents in the rhizomes of Curcuma longa. Methods: A variety of silica gel column chromatography, Sephadex LH-20 gel column chromatography, and HPLC methods were used for the separation and purification of chemical composition. Their structures were established on the basis of physicochemical property and spectral data. Results: Thirteen compounds were obtained and identified as 5-hydroxyl-bisabolon-9-one (1), cyclocurcumin (2), demethoxyl cyclocurcumin (3), isodemethoxyl cyclocurcumin (4), curcumin (5), demethoxyl curcumin (6), methyl ferulate (7), vanillin (8), 4-hydroxyl benzoic aldehyde (9), 4-(4-hydroxyl phenyl)-2-butanone (10), 4-(4-hydroxyl-3-methoxyl phenyl)-2-butanone (11), 4-(4-hydroxyl phenyl)-3- buten-2-one (12), and 4-(4-hydroxyl-3-methoxyl phenyl)-3-buten-2-one (13). Conclusion: Compound 1 is obtained as a new compound named 5-hydroxyl-bisabolon-9-one without reported in literature until now and compound 4 is first isolated from this plant.
