Application of blending raw materials in quality consistency control of Qianlie Shule Capsule
10.7501/j.issn.0253-2670.2016.08.011
- Author:
Wen-Jing YIN
1
Author Information
1. Jiangxi University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Blend;
Consistency;
Epimedin C;
HPLC;
Icariine;
Qianlie Shule Capsule
- From:
Chinese Traditional and Herbal Drugs
2016;47(8):1315-1320
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To develop a method for controlling the quality consistency of Qianlie Shule Capsule (QSC) by blending raw marerials. Methods: Blending raw materials were blended by medicine calculator V2. The content differences of epimedin C and icariine in QSC made from raw materials and their mixtures were compared. Results: The RSD of index component epimedin C from blended and raw materials were 11.2% and 82.5%, the RSD of icariine were 8.70% and 35.5%, the difference between index components decreased obviously, and it showed that the quality consistency in QSC was greatly increased. Conclusion: Using the method to control the quality coherence of Chinese patent medicine has the obvious results, it is easy to operate and suitable for actual production.
