Chemical constituents of Gymnotheca chinensis
10.7501/j.issn.0253-2670.2016.10.007
- Author:
Shi-Ji XIAO
1
Author Information
1. School of Pharmacy, Zunyi Medical University
- Publication Type:Journal Article
- Keywords:
Gymnotheca chinensis Decne.;
Nitrogen compound;
Polymethoxy flavonoid;
Sesquiterpene;
Stigmasterone
- From:
Chinese Traditional and Herbal Drugs
2016;47(10):1665-1669
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To further study the chemical constituents of Gymnotheca chinensis. Methods: The compounds were isolated and purified by silica gel column chromatography and preparative HPLC, and their structures were elucidated by spectral analysis. Results: Sixteen compounds were isolated and identified as 2-(1-hydroxy-4-oxo-cyclohexa-2,5-dienyl)-acetonitrile (1), N-benzoyl-2-hydroxyltyramine (2), N-benzoyltyramine (3), N-benzoyl-2-phenylethylamine (4), 7,4'-dimethoxykaemferol (5), nobiletin (6), tangeretin (7), curculonone A (8), 6-hydroxy-4,7-megastigmadien-3,9-dione (9), 5,6-epoxy-3-hydroxy-7-megastigmen-9-one (10), 9-hydroxy-4-megastigmen-3-one (11), 9-hydroxy-4,7-megastigmadien-3-one (12), loliolide (13), 6β-hydroxy-stigmasta-4-en-3-one (14), 6β-hydroxy- stigmasta-4,22-dien-3-one (15), and 3β-hydroxy-stigmasta-5-ene-7-one (16). Conclusion: Compounds 1 and 2 are new natural products, and the others are isolated from this genus for the first time.