Chemical constituents of Isodon flavidus produced in Leishan
10.7501/j.issn.0253-2670.2016.10.005
- Author:
Ya-Hua LIU
1
Author Information
1. Guiyang College of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Isodon flavidus (Hand. -Mazz.) Hara.;
Lophanic acid;
Oleanolic acid;
Sesamin;
Ursolic acid
- From:
Chinese Traditional and Herbal Drugs
2016;47(10):1657-1660
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents of Isodon flavidus. Methods: All compounds were isolated and purified by silica gel, Sephadex LH-20, and MCI column chromatography. Their structures were elucidated by analysis on the physicochemical properties and spectral data. Results: Nine compounds were obtained from the Miao medicine I. flavidus and respectively elucidated as lophanic acid (1), isopimara-7,15-dien-19-oic acid (2), isopimara-7,15-dien-3β-ol (3), rubesanolide D (4), ursolic acid (5), β-sitosterol (6), oleanolic acid (7), 2α,3α-dihydroxy-12-ene-28-oic acid (8), and sesamin (9). Conclusion: Compounds 1-5 and 8-9 are isolated from this plant for the first time, compound 3 is isolated from the plants of Rabdosia (BL.) Hassk for the first time.
