- Author:
Heung Yeol KIM
1
;
Jong Hyun YOON
;
Eun Byul CHO
;
Eun Ju PARK
;
Kwang Ho KIM
;
Kwang Joong KIM
Author Information
- Publication Type:Case Report
- Keywords: Giant cells; Spitzoid melanoma
- MeSH: Ankle; Diagnosis; Diagnostic Errors; Giant Cells; Melanoma*; Nevus, Epithelioid and Spindle Cell; Pigmentation
- From:Annals of Dermatology 2015;27(2):206-209
- CountryRepublic of Korea
- Language:English
- Abstract: Spitzoid melanoma is a subtype of melanoma that, clinically and histologically, resembles a Spitz nevus. Clinically, spitzoid melanomas usually evolve from amelanotic nodular lesions, growing to 1 cm or more in diameter. They often remain clinically undiagnosed because of their wide variety of clinical appearances and a lack of pigmentation. Distinguishing a Spitz nevus from a spitzoid melanoma can be extremely difficult. Features that favor the diagnosis of a spitzoid melanoma are asymmetrical shape, diameter greater than 1 cm, a lesion with a deep invasive component, and a high degree of cytologic atypia. There have been only rare reports in the literature of the presence of giant cells in malignant melanoma, and the presence of these cells may result in its misdiagnosis as a histiocytic tumor. We present a case of spitzoid melanoma on the right ankle of a 22-year-old-woman.