Study on pharmacodynamic material basis and mechanism of Shufeng Jiedu Capsule
10.7501/j.issn.0253-2670.2016.12.001
- Author:
Tie-Jun ZHANG
1
Author Information
1. Tianjin Institute of Pharmaceutical Research
- Publication Type:Journal Article
- Keywords:
Chemical components;
Pharmacodynamic material basis;
Quality control;
Quality standard;
Shufeng Jiedu Capsule
- From:
Chinese Traditional and Herbal Drugs
2016;47(12):2019-2026
- CountryChina
- Language:Chinese
-
Abstract:
The pharmacodynamic material basis of Shufeng Jiedu Capsule (SJC) was identified and the mechanism was explained. Ninety-four compounds were identified in SJC and 10 compounds were determined to be the anti-inflammatory ingredients by screening experiments. The mechanism of multi-component, multi-targets, and multi-pathways of SJC which provided a theoretical and experimental basis for the standards of quality control and the clinical application was elucidated by in vivo experiments, network pharmacology, and genomics.
