Research progress in chemical constituents, pharmacological effects, and clinical applications of Daturae Flos
10.7501/j.issn.0253-2670.2016.19.026
- Author:
Jia-Nan JING
1
Author Information
1. Key Laboratory of Base and Application of Bei Chinese Materia Medica, Heilongjiang Key Laboratory of TCM Pharmacodynamic Materia Bases, Heilongjiang University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Alkaloids;
Anti-inflammation activity;
Anti-itching effect;
Daturae Flos;
Flavonoids;
Psoriasis;
Withanolides
- From:
Chinese Traditional and Herbal Drugs
2016;47(19):3513-3521
- CountryChina
- Language:Chinese
-
Abstract:
Daturae Flos (flowers of Datura metel) is recorded by Chinese Pharmacopoeia for its important medicinal property. The most characteristic chemical constituents in Daturae Flos are withanolides, flavonoids, and alkaloids. There are also sesquiterpenoids, phenolic acid, and lignans in it. Daturae Flos has various pharmacological activities, such as anti-inflammation, anti-itching, cytoprotection, antibacterial effects, antioxidation, and so on. Daturae Flos also has the effect on epithelial cells mitosis and skin keratinization, immune system, central nervous system, cardiovascular system, and respiratory system. It is usually used to treat psoriasis, chronic tracheitis, asthma, infantile pneumonia, Parkinson disease, and rheumatism. In this paper, we summarize the chemical composition, pharmacyological effects, and clinical curative effect of Daturae Flos to prompt the development and utilization of them.
