Chemical constituents from canes of Schisandra sphenanthera
10.7501/j.issn.0253-2670.2016.19.005
- Author:
Ze-Hao HUANG
1
Author Information
1. Department of Pharmacy, Fujian University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Lignans;
Schisandra sphenanthera Rehd. et Wils;
She-medicine;
Sphendilactone;
Triterpenes
- From:
Chinese Traditional and Herbal Drugs
2016;47(19):3374-3378
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents from the canes of Schisandra sphenanthera. Methods: The compounds were isolated and purified by chromatography on silica gel. Their structures were elucidated on the basis of spectroscopic methods, including MS, 1D, and 2D NMR spectral techniques. Results: Thirteen compounds were isolated from 95% ethanol extract in the canes of S. sphenanthera, including six lignans, six triterpenes, and one steroid and their structures were identified as sphendilactone (1), kadsulactone (2), schisanlactone E (3), 12-β-hydroxycoccinic acid (4), schizandronic acid (5), schisanbilactone A (6), β-sitosterol (7), meso-dihydroguaiaretic acid (8), deoxychizandrin (9), schizantherin A (10), schisanhenol B (11), γ-schizandrin (12), and R-(+)-angeloygomisin M1 (13). Conclusion: Among them, one new triterpene is named as sphendilactone (1). Schisanhenol B, deoxychizandrin, R-(+)-angeloygomisin M1, kadsulactone, schisanlactone E, 12β-hydroxycoccinic acid, and schisanbilactone A are isolated from this plant for the first time.
