A new organic acid from Lonicerae Japonicae Caulis produced in Shandong
10.7501/j.issn.0253-2670.2016.21.002
- Author:
Xian-Hui JIA
1
Author Information
1. Key Laboratory for Rare Disease of Shandong Province, Institute of Materia Medica, Shandong Academy of Medical Science
- Publication Type:Journal Article
- Keywords:
Loganin;
Lonicerae Japonicae Caulis;
Loniceric acid ester;
Ochnaflavone;
β-daucosterol
- From:
Chinese Traditional and Herbal Drugs
2016;47(21):3766-3768
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents of Lonicerae Japonicae Caulis produced in Shandong Province. Methods: Compounds were isolated and purified by repeated column chromatographies including silica gel, MCI-gel resin, Sephadex LH-20, and so on. Their structures were elucidated by spectral data, including extensive 1D and 2D NMR techniques. Results: Four compounds were obtained and identified as 11,14,15-trihydroxy-12-octadecenoic acid methyl ester (1), ochnaflavone (2), β-daucosterol (3), and loganin (4). Conclusion: Compound 1 is a new organic acid named as loniceric acid ester, and compound 2 is isolated from Lonicerae Japonicae Caulis for the first time.